Research Papers §
- Senolytic and senomorphic secondary metabolites as therapeutic agents in Drosophila melanogaster models of Parkinson’s disease.
- In-vivo screening implicates endoribonuclease Regnase-1 in modulating senescence-associated lysosomal changes.
- Cellular Senescence Contributes to Large Elastic Artery Stiffening and Endothelial Dysfunction With Aging: Amelioration With Senolytic Treatment.
- Cellular Senescence and Frailty in Transplantation.
- Strategies for senolytic drug discovery.
- Redox signaling and modulation in ageing.
- Vascular Ageing: Mechanisms, Risk Factors, and Treatment Strategies.
- Endometrial receptivity in women of advanced age: an underrated factor in infertility.
- Cellular senescence in glioma.
- Therapeutic Perspectives for Inflammation and Senescence in Osteoarthritis Using Mesenchymal Stem Cells, Mesenchymal Stem Cell-Derived Extracellular Vesicles and Senolytic Agents.
- Impact of Geroscience on Therapeutic Strategies for Older Adults With Cardiovascular Disease: JACC Scientific Statement.
- The Role of Oxidative Stress and Cellular Senescence in the Pathogenesis of Metabolic Associated Fatty Liver Disease and Related Hepatocellular Carcinoma.
- Senopathies-Diseases Associated with Cellular Senescence.
- A short dasatinib and quercetin treatment is sufficient to reinstate potent adult neuroregenesis in the aged killifish.
- Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop.
- Increased cell senescence in human metabolic disorders.
- Discovery of senolytics using machine learning.
- Aging and chronic inflammation: highlights from a multidisciplinary workshop.
- Cell Survival, Death, and Proliferation in Senescent and Cancer Cells: the Role of (Poly)phenols.
- Long-term dasatinib plus quercetin effects on aging outcomes and inflammation in nonhuman primates: implications for senolytic clinical trial design.
- The ageing immune system as a potential target of senolytics.
- Challenges in the Vaccination of the Elderly and Strategies for Improvement.
- Inflammaging and Immunosenescence as Part of Skin Aging-A Narrative Review.
- Senescent Cells: A Therapeutic Target in Cardiovascular Diseases.
- MAPK Pathway.
- Drugs against metabolic diseases as potential senotherapeutics for aging-related respiratory diseases.
- Cellular senescence in skin-related research: Targeted signaling pathways and naturally occurring therapeutic agents.
- Emerging Therapeutic Approaches to Target the Dark Side of Senescent Cells: New Hopes to Treat Aging as a Disease and to Delay Age-Related Pathologies.
- Effect of Nrf2 loss on senescence and cognition of tau-based P301S mice.
- Effect of peripheral cellular senescence on brain aging and cognitive decline.
- Cellular senescence of renal tubular epithelial cells in renal fibrosis.
- Targeting Mitochondria to Control Ageing and Senescence.
- The Potential of Senescence as a Target for Developing Anticancer Therapy.
- Hallmarks and Biomarkers of Skin Senescence: An Updated Review of Skin Senotherapeutics.
- An Updated Overview on the Role of Small Molecules and Natural Compounds in the “Young Science” of Rejuvenation.
- Molecular mechanisms of alveolar epithelial cell senescence and idiopathic pulmonary fibrosis: a narrative review.
- Targeting senescent cells for a healthier longevity: the roadmap for an era of global aging.
- Radiation-induced senescence: therapeutic opportunities.
- Endothelial senescence in vascular diseases: current understanding and future opportunities in senotherapeutics.
- Mitochondrial Aging and Senolytic Natural Products with Protective Potential.
- Senolytic Therapy: A Potential Approach for the Elimination of Oncogene-Induced Senescent HPV-Positive Cells.
- A Unified Model of Age-Related Cardiovascular Disease.
- Senescent AECⅡ and the implication for idiopathic pulmonary fibrosis treatment.
- Anthracycline-induced cardiotoxicity and senescence.
- Aging and Mesenchymal Stem Cells: Basic Concepts, Challenges and Strategies.
- Major depression and the biological hallmarks of aging.
- Senotherapeutics and Their Molecular Mechanism for Improving Aging.
- COVID-19 and cellular senescence.
- Nutritional senolytics and senomorphics: Implications to immune cells metabolism and aging - from theory to practice.
- From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs.
- Targeting cellular senescence in metabolic disease.
- Potential Role of Polyphenolic Flavonoids as Senotherapeutic Agents in Degenerative Diseases and Geroprotection.
- Targeting senescence as an anticancer therapy.
- Senescence and cancer - role and therapeutic opportunities.
- A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.
- Cellular senescence and senolytics: the path to the clinic.
- Cellular senescence: the good, the bad and the unknown.
- Cellular senescence: a key therapeutic target in aging and diseases.
- Translation of Cellular Senescence to Novel Therapeutics: Insights From Alternative Tools and Models.
- Mitochondria-targeted senotherapeutic interventions.
- The Achilles’ heel of cancer survivors: fundamentals of accelerated cellular senescence.
- p19ARF, and p21 in Organ Development and Homeostasis.
- Cellular Senescence: Molecular Targets, Biomarkers, and Senolytic Drugs.