Researchers: Klára Daďová, Miroslav Petr, James J Tufano, Lenka Sontáková, Eva Krauzová, Marek Štěpán, Michaela Šiklová, Michal Šteffl
PURPOSE: In our study, we examined changes in short-term episodic memory and brain-derived neurotrophic factor (BDNF) in women after an exercise program alone or in combination with omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation. PATIENTS AND METHODS: Fifty-five healthy elderly women (65-80 years) were randomly split into two groups: in the first group were women attending an exercise program while taking wax esters-rich oil (Calanus) supplementation (n = 28) and in the other group were women undergoing the same exercise program while taking placebo (n = 27). The 16-week exercise program consisted of functional circuit training (twice a week) and Nordic walking lessons (once a week). Short-term episodic memory was evaluated by the Czech screening Test “Pojmenování OBrázků A jejich Vybavení” (POBAV) baseline and after the program lasting 16 weeks. RESULTS: Our results show that short-term memory significantly improved following the exercise program, but there was no added value in using n-3 PUFA supplements. BDNF values did not differ between baseline and follow-up in either group. However, there was a statistically significant positive relationship between relative change (%) in the POBAV test and VO2peak in the placebo group (r = 0.49). CONCLUSION: Despite the added value of n-3 PUFA supplementation not being proven, our results may strengthen the importance of physical activity in averting age-related memory decline and dementia.
References
- Effects of Dietary Food Components on Cognitive Functions in Older Adults.
- Omega-3 fatty acids and dementia.
- Physical exercise in the prevention and treatment of Alzheimer’s disease.
- Exercise for Brain Health: An Investigation into the Underlying Mechanisms Guided by Dose.
- Docosahexaenoic acid-concentrated fish oil supplementation in subjects with mild cognitive impairment (MCI): a 12-month randomised, double-blind, placebo-controlled trial.
- Effects of Combined Resistance and Power Training on Cognitive Function in Older Women: A Randomized Controlled Trial.