Researchers: Matteo Tosato, Francesca Ciciarello, Maria Beatrice Zazzara, Cristina Pais, Giulia Savera, Anna Picca, Vincenzo Galluzzo, Hélio José Coelho-Júnior, Riccardo Calvani, Emanuele Marzetti, Francesco Landi, Gemelli Against COVID-19 Post-Acute Care Team
The persistence of COVID-19 symptoms weeks or months after an initial SARS-CoV-2 infection has become one of the most burdensome legacies of the pandemic. This condition, known as long COVID syndrome, affects many persons of all age groups and is associated with substantial reductions of quality of life. Several mechanisms may be involved in long COVID syndrome, including chronic inflammation, metabolic perturbations, endothelial dysfunction, and gut dysbiosis. These pathogenic mechanisms overlap with those of the aging process and may aggravate pre-existing degenerative conditions. This review discusses bioactive foods, supplements, and nutraceuticals as possible interventions against long COVID syndrome.