Research Papers §
- Geroprotective interventions in the 3xTg mouse model of Alzheimer’s disease.
- TAZ Signaling Inhibitors on Drosophila melanogaster Model.
- Biological ageing with HIV infection: evaluating the geroscience hypothesis.
- New insight into dyslipidemia-induced cellular senescence in atherosclerosis.
- Senotherapeutics in Cancer and HIV.
- Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans.
- The role of NAD and NAD precursors on longevity and lifespan modulation in the budding yeast, Saccharomyces cerevisiae.
- Geroprotectors and Skeletal Health: Beyond the Headlines.
- Senescence and the tumor-immune landscape: Implications for cancer immunotherapy.
- Senolytic drugs: Beyond the promise and the hype.
- Role of circulating molecules in age-related cardiovascular and metabolic disorders.
- The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions.
- Strategies for Targeting Senescent Cells in Human Disease.
- Epigenetic dysregulation in cardiovascular aging and disease.
- Skeletal muscle aging, cellular senescence, and senotherapeutics: Current knowledge and future directions.
- A geroscience motivated approach to treat Alzheimer’s disease: Senolytics move to clinical trials.
- Navitoclax improves functional hyperemia in aged mice.
- The redox-senescence axis and its therapeutic targeting.
- Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors.
- Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy.
- Treating Senescence like Cancer: Novel Perspectives in Senotherapy of Chronic Diseases.
- Stem Cells of the Aging Brain.
- Astaxanthin as a Putative Geroprotector: Molecular Basis and Focus on Brain Aging.
- Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast.
- Terpenoids as Potential Geroprotectors.
- Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections.
- A toolbox for the longitudinal assessment of healthspan in aging mice.
- Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast.
- Maximizing Longevity and Healthspan: Multiple Approaches All Converging on Autophagy.
- Senotherapeutics: emerging strategy for healthy aging and age-related disease.
- Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions.
- Translating Measures of Biological Aging to Test Effectiveness of Geroprotective Interventions: What Can We Learn from Research on Telomeres?
- Towards natural mimetics of metformin and rapamycin.
- Geroprotectors: A Unified Concept and Screening Approaches.
- Geroprotective and Radioprotective Activity of Quercetin, (-)-Epicatechin, and Ibuprofen in Drosophila melanogaster.
- In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state.
- Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic.
- Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes.
- Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease.